Adding a certain compound to certain chemical reactions, such as: 69393-72-2, Benzo[d][1,3]dioxol-4-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, COA of Formula: C7H6O3, blongs to alcohols-buliding-blocks compound. COA of Formula: C7H6O3
a) 4-hydroxy-5-(4-propylpiperazinylmethyl)-1,3-benzodioxole Aqueous formaldehyde (37%; 3.67 g, 45.3 mmol) was added dropwise to a stirred solution of 4-hydroxy-1,3-benzodioxole (5.2 g, 37.8 mmol) and N-propylpiperazine (5.8 g, 45.3 mmol) in acetonitrile (25 ml). The reaction mixture was stirred at room temperature for one hour and evaporated in vacuo. The remaining oil (13.0 g) was purified chromatographically (with ethylacetate/methanol=9/1 (v/v) as an eluent to give 4-hydroxy-5-(4-propylpiperazinylmethyl)-1,3-benzodioxole (5.9 g, 56% yield; compound No. 25), m.p. 115-117 C.
The synthetic route of 69393-72-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Duphar International Research B.V.; US5281595; (1994); A;,
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