Electric Literature of 13588-28-8, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 13588-28-8, name is 2-(2-Methoxypropoxy)propan-1-ol. A new synthetic method of this compound is introduced below.
In a 500 mL flask, feed NaOH tablets 55. 2 g (relative to the following DPMI moles,Equivalent to 1. 5 moles)And 1-bromo-3-methylbutane(Manufactured by Yancheng Longsheng Chemical Co., Ltd.) (hereinafter also referred to as “IABr”) 163.5 g (relative to the following DPMI moles,Equivalent to 1. 2 moles)Start stirring.After raising the liquid temperature to 45 C,While keeping the temperature inside the system at 45 C,DPM133. 7 g was added dropwise over 6 hours.Thereafter,Stirring was carried out while maintaining a 45 C condition.In addition,The low boiling compounds produced in the above reaction were measured using a gas flow meter and gas chromatography3-methyl-1-butene.To the reaction solution was added water 155. 7 g was subjected to extraction / separation,The results of the analysis of the obtained organic phase 222. 5 g using gas chromatography,Got 125. 0gOf dipropylene glycol methyl isopentyl ether(Isomer mixture) (hereinafter also referred to as “”DPMIA”).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,13588-28-8, 2-(2-Methoxypropoxy)propan-1-ol, and friends who are interested can also refer to it.
Reference:
Patent; Daicel Corporation; Mori, Atsushi; (9 pag.)CN105503545; (2016); A;,
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