Application of 1051899-73-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 1051899-73-0, name is (3-Amino-2-fluorophenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
A solution of 2,4-dichloropyrimidine (300 mg, 2.01 mmol), (3-amino-2- fluorophenyl)methanol (256 mg, 1.81 mmol) and triethylamine (309 mul, 2.22 mmol) in 2- propanol (5 ml) was stirred over a period of 15 hrs at 90C as described in Method 1. Work-up and purification gave (3-(2-chloropyrimidin-4-ylamino)-2 -fluorophenyl) methanol (206 mg, 40.3 %) as a white solid. Mass Spectrum: M+H+ 254. NMR Spectrum (DMSOdbeta): 4.44 (s, 2H), 5.39 (bs, IH), 6.51 (bs, IH), 7.13 (ddd, IH), 7.30 (dd, IH), 7.36 (dd, IH), 8.09 (d, IH), 9.41 (bs, IH)
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1051899-73-0, (3-Amino-2-fluorophenyl)methanol.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2008/104754; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts