Related Products of 72995-94-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 72995-94-9, name is 14-Bromotetradecan-1-ol, molecular formula is C14H29BrO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
A mixture of 14-bromotetradecan-1-ol (700 mg, 2.38 mmol) and DAST (0.63 ml_, 4.76 mmol) was heated at 35 C for 4h. The reaction mixture was poured into water and extracted with DCM (x3). The combined organic extracts were washed with brine, dried over magnesium sulfate, filtered and the solvent was removed under reduced pressure. The residue was purified by flash chromatography (hexanes/diethyl ether) to yield the title compound (422 mg, 60%) as a colourless oil. 1 H NMR d (400 MHz, CDCI3): 1.21-1.34 (m, 16H), 1.35-1.47 (m, 4H), 1.60-1 .78 (m, 2H), 1.80-1 .92 (m, 2H), 3.41 (t, J=6.9 Hz, 2H), 4.38 (t, J=6.2 Hz, 1 H), 4.50 (t, J=6.2 Hz, 1 H).
According to the analysis of related databases, 72995-94-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ALMIRALL, S.A.; BACH TANA, Jordi; ESTEVE TRIAS, Cristina; MIR CEPEDA, Marta; (187 pag.)WO2019/115405; (2019); A1;,
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