Electric Literature of 13651-14-4 , The common heterocyclic compound, 13651-14-4, name is (2,3-Dimethylphenyl)methanol, molecular formula is C9H12O, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: A mixture containing benzyl alcohol(1 mmol), beta-naphthol (1 mmol), 4-hydroxycoumarin(1 mmol), 4 mmol % of [BDBDMIm]Br, and 0.05 g of CAN was stirred at room temperature for the requiredreaction times. Progress of the reaction was monitoredby TLC (EtOAc : petroleum ether, 1 : 3). Uponcompletion of the process the product was extractedwith CHCl3/H2O. The organic phases was separatedand the solvent evaporated. Crystallization of theresidue gave the pure product. The aqueous phase wasconcentrated under reduced pressure, washed withEt2O, and evaporated under reduced pressure torecover the ionic liquid for subsequent use.
The synthetic route of 13651-14-4 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Gharib; Nikpassand; Russian Journal of General Chemistry; vol. 86; 12; (2016); p. 2759 – 2767; Zh. Obshch. Khim.; vol. 86; (2016); p. 2759 – 2767,9;,
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