Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 14426-21-2, name is Diethanolamine hydrochloride. A new synthetic method of this compound is introduced below., SDS of cas: 14426-21-2
EXAMPLE 6 N,N-di-[2-(3,4,5-trimethoxybenzoyloxy)ethyl]taurine A mixture of 14 g of diethanolamine hydrochloride, 200 ml of dimethoxyethane and 47 g of 3,4,5-trimethoxybenzoyl chloride was left at ambient temperature for one night under agitation. The excess HCl was removed with a current of nitrogen, and the solution then evaporated under reduced pressure and taken up in 300 ml of anhydrous ethyl alcohol. 14 G of sodium ethoxide in 200 ml of absolute alcohol was added under cooling, then 21 g of sodium bromoethanesulphonate and 1.7 g of potassium iodide. After 120 hours at ambient temperature, the inorganic salts were filtered off and the solution concentrated under reduced pressure to a small volume. The mixture was then left to stand for one night, then filtered and crystallized from methanol. The product had a melting point of 179-182 C. and was identical to that obtained in Example 2.
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Reference:
Patent; Laboratorio Chimico Farmaceutico CAUSYTH S.p.A.; US4259332; (1981); A;,
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