I found the field of Chemistry very interesting. Saw the article A Novel Approach to N-Tf 2-Aryl-2,3-Dihydroquinolin-4(1H)-ones via a Ligand-Free Pd(II)-Catalyzed Oxidative Aza-Michael Cyclization published in 2021. Safety of (4-Methoxyphenyl)methanol, Reprint Addresses Kim, NJ (corresponding author), Kyung Hee Univ, Coll Pharm, 26 Kyungheedae Ro, Seoul 02447, South Korea.; Park, BY; Kim, NJ (corresponding author), Kyung Hee Univ, Dept Life & Nanopharmaceut Sci, 26 Kyungheedae Ro, Seoul 02447, South Korea.. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol
2-Aryl-2,3-dihydroquinolin-4(1H)-ones have recently been identified as important structures with potent biological activities such as antitumor and antidiabetic effect. Herein, a total of 25 novel N-Tf 2-aryl-2,3-dihydroquinolin-4(1H)-ones were expediently synthesized via the oxidative aza-Michael cyclization of N-Tf-2 ‘-aminodihydrochalcones by ligand-free palladium(II) catalysis. This study presents a new synthetic approach to yield N-Tf 2-aryl-2,3-dihydroquinolin-4(1H)-ones, which can be easily transformed into pharmacologically interesting aza-flavanones and other N-heterocycles, such as quinolines and tetrahydroquinolines, in yields up to 84 %. This methodology has various advantages, which includes short reaction times under mild conditions and suitable functional group tolerance. Furthermore, a plausible mechanism was proposed and demonstrated by kinetic analysis.
Welcome to talk about 105-13-5, If you have any questions, you can contact Kim, YM; Yoo, HS; Son, SH; Kim, GY; Jang, HJ; Kim, DH; Kim, SD; Park, BY; Kim, NJ or send Email.. Safety of (4-Methoxyphenyl)methanol
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