Chemistry Milestones Of C8H10O2

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SDS of cas: 105-13-5. Lu, XL; Qiu, YY; Yang, BC; He, HB; Gao, SH in [Lu, Xiao-Long; Qiu, Yuanyou; Yang, Baochao; Gao, Shuanhu] East China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, 3663N Zhongshan Rog, Shanghai 200062, Peoples R China; [He, Haibing; Gao, Shuanhu] East China Normal Univ, Shanghai Engn Res Ctr Mol Therapeut & New Drug De, 3663N Zhongshan Rd, Shanghai 200062, Peoples R China published Asymmetric total synthesis of (+)-xestoquinone and (+)-adociaquinones A and B in 2021, Cited 76. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5.

The asymmetric total synthesis of (+)-xestoquinone and (+)-adociaquinones A and B was achieved in 6-7 steps using an easily accessible meso-cyclohexadienone derivative. The [6,6]-bicyclic decalin B-C ring and the all-carbon quaternary stereocenter at C-6 were prepared via a desymmetric intramolecular Michael reaction with up to 97% ee. The naphthalene diol D-E ring was constructed through a sequence of Ti(Oi-Pr)(4)-promoted photoenolization/Diels-Alder, dehydration, and aromatization reactions. This asymmetric strategy provides a scalable route to prepare target molecules and their derivatives for further biological studies.

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Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts