Recently I am researching about ASYMMETRIC CONJUGATE ADDITION; ENANTIOSELECTIVE SYNTHESIS; TETRAHYDROPYRAN; HYDRATION; ACIDS, Saw an article supported by the Platform Project for Supporting in Drug Discovery and Life Science Research from Japan Agency for Medical Research and Development (AMED).JapanJapan Agency for Medical Research and Development (AMED). Formula: C8H10O2. Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Inatomi, S; Takayanagi, Y; Watanabe, K; Toita, A; Yamakoshi, H; Nakamura, S. The CAS is 105-13-5. Through research, I have a further understanding and discovery of (4-Methoxyphenyl)methanol
The scope and limitations of the diastereoselective 1,4-addition reaction of primary alcohols to gamma-alkoxy-alpha,beta-unsaturated esters were investigated. We found that a variety of sodium alkoxides, generated from the corresponding primary alcohols with NaH, underwent 1,4-addition reactions with (E)-enoates in CH(2)Cl(2)at -23 degrees C to give beta-alkoxy esters in modest yields with good to excellentsyn-selectivity, whereas stereoselectivity was not observed with the use of glycerol derivatives as nucleophiles. Cyclic acetal protection was found to play a pivotal role for the reaction to proceed.
Welcome to talk about 105-13-5, If you have any questions, you can contact Inatomi, S; Takayanagi, Y; Watanabe, K; Toita, A; Yamakoshi, H; Nakamura, S or send Email.. Formula: C8H10O2
Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts