An article HFIP-catalyzed direct dehydroxydifluoroalkylation of benzylic and allylic alcohols with difluoroenoxysilanes WOS:000613461100020 published article about FLUORINATED ALCOHOLS; SOLVENTS; ACCESS; BENZYLATION; ALLYLATION; REAGENTS; ETHERS in [Li, Jinshan; Xi, Wenxue; Zhong, Rong; Yang, Jianguo; Wang, Lei; Wang, Zhiming] Taizhou Univ, Adv Res Inst, 1139 Shifu Ave, Taizhou 318000, Peoples R China; [Li, Jinshan; Xi, Wenxue; Zhong, Rong; Yang, Jianguo; Wang, Lei; Wang, Zhiming] Taizhou Univ, Dept Chem, 1139 Shifu Ave, Taizhou 318000, Peoples R China; [Ding, Hanfeng] Zhejiang Univ, Dept Chem, Hangzhou 310058, Peoples R China in 2021, Cited 49. Computed Properties of C8H10O2. The Name is (4-Methoxyphenyl)methanol. Through research, I have a further understanding and discovery of 105-13-5
Hexafluoroisopropanol (HFIP)-catalyzed direct dehydroxydifluoro-alkylation of benzylic and allylic alcohols with difluoroenoxysilanes is developed. This procedure enables the synthesis of a broad range of alpha,alpha-difluoroketones, a class of highly valuable intermediates and building blocks in medicinal and organic chemistry. Here, we have demonstrated for the first time that HFIP could act as a powerful catalyst for fluorinated carbon-carbon bond formation. The application of this protocol in late-stage dehydroxydifluoroalkylation of potentially bioactive drugs and natural products has also been carried out.
About (4-Methoxyphenyl)methanol, If you have any questions, you can contact Li, JS; Xi, WX; Zhong, R; Yang, JG; Wang, L; Ding, HF; Wang, ZM or concate me.. Computed Properties of C8H10O2
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