Electric Literature of 3840-31-1 ,Some common heterocyclic compound, 3840-31-1, molecular formula is C10H14O4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
General procedure: To 3.5 g (53 mmol) of 85% potassiumhydroxide was added a solution of 10 g (50.5 mmol) ofalcohol 8 in 40 mL of DMSO, and the mixture washeated at 50-70 while stirring till the dissolution ofK, then the heating was switched off. On coolingthe mixture to room temperature a solution of 7 g(56.9 mmol) of allyl bromide in 10 mL of DMSO wasadded, and the mixture was stirred for 16 h. Then themixture was heated (5060) at stirring till thecompletion of the reaction (5 h). The mixture wasdiluted with 200 mL of water, the reaction product wasextracted into ethyl acetate (4 × 50 mL). The organicphase was washed with water, dried with Na2SO4, thesolvent was distilled off, the residue was dried in avacuum.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 3840-31-1, (3,4,5-Trimethoxyphenyl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Potapov; Panov; Musalov; Zhivet?eva; Musalova; Khabibulina; Amosova; Russian Journal of Organic Chemistry; vol. 52; 11; (2016); p. 1571 – 1575; Zh. Org. Khim.; vol. 52; 11; (2016); p. 1579 – 1583,5;,
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