Adding a certain compound to certain chemical reactions, such as: 62285-58-9, (2,6-Dimethylphenyl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: (2,6-Dimethylphenyl)methanol, blongs to alcohols-buliding-blocks compound. Recommanded Product: (2,6-Dimethylphenyl)methanol
General procedure 1 (GPl) Step l:To the commercially available alcohols (0.288 mmol), placed in vials (20 mL) equipped with screw caps, were added a solution of 2-(4-carboxymethyl-phenylsulfanylmethyl)-benzoic acid 2,2,2-trichloro-ethyl ester (125mg, 0.288mmol), EDCxHCl (83mg, 0.435mmol), DMAP (3.5mg, 0.029mmol) and DCM (4 mL). The reaction mixtures were stirred at rt overnight. The mixtures were quenched with 0.25M HCl (4 mL) and the two phases were separated through phase separators. The organic phases were concentrated and used without further purification into the next step.; Example 33 2-[4-(2,6-Dimethyl-benzyloxycarbonylmethyl)-phenylsulfanylmethyl]-benzoic acidThe titled compound was prepared according to GPl. Step 1: Using (2,6-dimethyl-phenyl)- methanol as the alcohol. Step 2: The reaction time was 2 days. Yield: 37mg (31 %). 1H NMR (600 MHz, (CD3)2SO, (CH3)2SO): delta 2.24 (s, 6H), 3.61 (s, 2H), 4.54 (s, 2H), 5.10 (s, 2H), 7.00 (d, 2H), 7.08-7.14 (m, 3H), 7.22 (d, 2H), 7.27-7.34 (m, 2H), 7.36-7.40 (m, IH), 7.82 (d, IH); Mass spectrum: M-H+ 419.
The synthetic route of 62285-58-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; ALBIREO AB; WO2008/108735; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts