9/16 News Extracurricular laboratory: Synthetic route of 13674-16-3

At the same time, in my other blogs, there are other synthetic methods of this type of compound,13674-16-3, Methyl 2-hydroxy-3-phenylpropanoate, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.13674-16-3, name is Methyl 2-hydroxy-3-phenylpropanoate, molecular formula is C10H12O3, molecular weight is 180.2, as common compound, the synthetic route is as follows.Recommanded Product: Methyl 2-hydroxy-3-phenylpropanoate

EXAMPLE 14 2-[4′-(2-Benzoyl-benzofuran-3-yl)-biphenyl-4-yloxy]-3-phenyl-propionic acid The title compound was prepared from 4′-(2-benzoyl-benzofuran-3-yl)-biphenyl-4-ol, and 3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h, and was obtained as a yellow solid, mp 159-161 C.; MS m/e 538 (M+); Analysis for: C36H26O5 Calc’d: C, 80.28; H, 4.86 Found: C, 80.15; H, 4.91.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,13674-16-3, Methyl 2-hydroxy-3-phenylpropanoate, and friends who are interested can also refer to it.

Reference:
Patent; American Home Products Corporation; US6232322; (2001); B1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts