16-Sep-21 News Share a compound : 1875-88-3

According to the analysis of related databases, 1875-88-3, the application of this compound in the production field has become more and more popular.

Application of 1875-88-3, Adding some certain compound to certain chemical reactions, such as: 1875-88-3, name is 2-(4-Chlorophenyl)ethanol,molecular formula is C8H9ClO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1875-88-3.

PREPARATION B-XI 2-(4-chloro)phenyl-1-mesyloxyethane To a stirring solution of 3.00 mL (22.16 mMol) 2-(4-chloro)phenyl-1-ethanol in 75 mL tetrahydrofuran at 0 C. were added 4.63 mL (33.24 mMol) triethylamine followed by 1.89 mL (24.38 mMol) methanesulfonyl chloride. The reaction mixture was allowed to stir at room temperature for 18 hours. The reaction mixture was then poured into water and extracted well with ethyl acetate. The organic phases were combined, washed with water, dried over sodium sulfate and concentrated under reduced pressure to give 5.18 gm (99.6%) of the title compound.

According to the analysis of related databases, 1875-88-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Eli Lilly and Company; US5962473; (1999); A;,
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