14 Sep 2021 News Extracurricular laboratory: Synthetic route of 927-74-2

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 927-74-2, 3-Butyn-1-ol, other downstream synthetic routes, hurry up and to see.

Application of 927-74-2, Adding some certain compound to certain chemical reactions, such as: 927-74-2, name is 3-Butyn-1-ol,molecular formula is C4H6O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 927-74-2.

General procedure: To a solution of 3-butyn-1-ol 10 (1.2 equiv.) in tert-BuOH (40 mL) and H2O (40 mL), CuSO4·5H2O (0.25 equiv.), sodium ascorbate (0.5 equiv.), aryl/alkyl azide 9 (1.1 equiv.) and triethylamine (1.0 equiv.) were added. The mixture was stirred at r.t. under N2 for 4 h, and then concentrated in vacuo. The residue was extracted with CH2Cl2 (3 × 30 mL). The organic layer was dried over MgSO4, filtered, and concentrated under reduced pressure. The obtained triazoles were used for the next reaction without further purification.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 927-74-2, 3-Butyn-1-ol, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Giofre, Salvatore V.; Romeo, Roberto; Carnovale, Caterina; Mancuso, Raffaella; Cirmi, Santa; Navarra, Michele; Garozzo, Adriana; Chiacchio, Maria A.; Molecules; vol. 20; 4; (2015); p. 5260 – 5275;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts