Application of 928-51-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 928-51-8, name is 4-Chlorobutan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 4-iodo-lH-pyrazole (3.88 g, 20 mmol) in CH3CN (0943) (140 mL) was added 4-chlorobutan-l-ol (3.3 g, 1.3eq), Cs2C03 (16.4 g, 60 mmol), and Nal (600 mg). The reaction mixture was heated at 50 C for 12 hour. The reaction mixture was filtered and the filtrate was evaporated. The residue was purified by chromatography (EtOAc/Hexanes: 1:1 to EtOAc) to afford 4-(4-iodo-lH-pyrazol-l- yl)butan-l-ol (4 g, 75%).
According to the analysis of related databases, 928-51-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; THE REGENTS OF THE UNIVERSITY OF MICHIGAN; WANG, Shaomeng; HU, Yang; QIN, Chong; XU, Fuming; HU, Jiantao; ZHOU, Bing; CHEN, Zhou; FERNANDEZ-SALAS, Ester; BAI, Longchuan; McEACHERN, Donna; (198 pag.)WO2018/52945; (2018); A1;,
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