Synthetic Route of 83647-43-2, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 83647-43-2 as follows.
2-methyl-3-bromobenzyl alcohol (7 g, 34 mmol) was added to 120 mL of acetonitrile,NBS (6.8 g, 38 mmoL) was added at room temperature,The reaction was stirred at room temperature for 3 h,The solvent was removed by concentration under reduced pressure.To the residue was added 150 mL of dichloromethane,Stir,filter,The filtrate was concentrated under reduced pressure.The crude product was obtained by silica gel column chromatography (PE / EA = 85/15) to obtain 7.3 g (yield: 76.5%) of 2-methyl-3,6-dibromobenzyl alcohol;
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,83647-43-2, its application will become more common.
Reference:
Patent; Chengdu Na Sheng Technology Co., Ltd.; Yan Gexin; Zhang Hui; Zhou Lihong; (15 pag.)CN106432214; (2017); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts