01/9/2021 News Extracurricular laboratory: Synthetic route of 80866-82-6

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 80866-82-6, 5-Bromo-2-methoxybenzyl alcohol.

Application of 80866-82-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 80866-82-6, name is 5-Bromo-2-methoxybenzyl alcohol. This compound has unique chemical properties. The synthetic route is as follows.

Reference Example 26 Imidazole (3.45 g) and t-butyldimethylchlorosilane (17.6 g) were added to a solution of 5-bromo-2-methoxybenzyl alcohol (10.0 g) in DMF (100 ml) under cooling with ice and the mixture was stirred for two hours. The reaction mixture was added to ice-cooled water and extracted with ethyl acetate. The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the filtrate was concentrated. The residue was purified by silica gel column chromatography (n-hexane-ethyl acetate) to obtain [(5-bromo-2-methoxybenzyl)oxy](t-butyl)dimethylsilane (15.2 g).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 80866-82-6, 5-Bromo-2-methoxybenzyl alcohol.

Reference:
Patent; Tomiyama, Hiroshi; Noda, Atsushi; Kitta, Kayoko; Kobayashi, Yoshinori; Imamura, Masakazu; Murakami, Takeshi; Ikegai, Kazuhiro; Suzuki, Takayuki; Kurosaki, Eiji; US2005/124555; (2005); A1;,
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