Reference of 616-29-5, Adding some certain compound to certain chemical reactions, such as: 616-29-5, name is 1,3-Diaminopropan-2-ol,molecular formula is C3H10N2O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 616-29-5.
1,3-diaminopropan-2-ol (3 g, 0.033 mol) was dissolved in methanol (300 ml) followed by the addition of triethylamine (33 ml dropwise) and di-tert-butyl dicarbonate [(BOC)2O] (21.793 g, 0.100 mol). The reaction medium was heated at 40-50 C. for 20 min then stirred at room temperature for 1 hour. After evaporation of the solvent, the colorless oil residue was purified by chromatography on silica gel (eluent: dichloromethane/methanol 95:5). The reaction yielded a colorless oil which crystallized slowly. Yield: quantitative Rf (dichloromethane/methanol 95:5): 0.70 IR: nuNH 3368 cm-1; nuCO carbamate 1690 cm-1 MP: 98-100 C. NMR (1H, CDCl3): 1.45 (multiplet, 18H, -CH3- (BOC)); 3.02 (sl, 1H, OH); 3.15-3.29 (multiplet, 4H, BOCNH-CH2-CH-CH2-NHBOC); 3.75 (m, 1H, BOCNH-CH2-CH-CH2-NHBOC); 5.16 (multiplet, 2H, -NHBOC). MS (MALDI-TOF): M+1=291 (M+H+); M+23=313 (M+Na+); M+39=329 (M+K+)
According to the analysis of related databases, 616-29-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Darteil, Raphael; Caumont-Bertrand, Karine; Najib, Jamila; US2006/69156; (2006); A1;,
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