Application of 16308-92-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 16308-92-2, name is (2,4-Dimethylphenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
General procedure: To a suspension of benzyl alcohol (1.1 g, 0.0101 mol), aniline (0.94 g, 0.0101 mol), and ethyl vinyl ether (0.728 g, 0.0101 mol) in a mixture of EtOAc:DMSO (6.0: 2.0 mL) was added T3P (2.0 mmol, 50% solution in ethyl acetate) at 0oC, and the resulting mixture was stirred at room temperature for 45 h. Progress of the reaction was monitored by TLC. The reaction mass was concentrated, the obtained residue was neutralized with 10% NaHCO3 solution, and then extracted with ethyl acetate (2 x 20 mL), the combined organic phase was washed with water and brine solution, and dried over anhydrous sodium sulphate. The organic phase was evaporated and the crude product was purified by column chromatography using silica gel mesh 100-200 (15% EtOAc in hexanes).
According to the analysis of related databases, 16308-92-2, the application of this compound in the production field has become more and more popular.
Reference:
Article; Narasimhamurthy, Kereyagalahally H.; Chandrappa, Siddappa; Kumar, Kothanahally S. Sharath; Swaroop, Toreshettahally R.; Rangappa, Kanchugarakoppal S.; Chemistry Letters; vol. 42; 9; (2013); p. 1073 – 1075;,
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