Synthetic Route of 1562-00-1, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1562-00-1, name is Sodium isethionate, molecular formula is C2H5NaO4S, molecular weight is 148.1135, as common compound, the synthetic route is as follows.
EXAMPLE 1 14.8 g Isethionic acid-Na and 150 mg NaOH and 100 ml of benzyl alcohol were reacted in a 250 ml round bottom flask with a distillation bridge and heated slowly at 180 to 200 C for about 3 hours. At this temperature, about 1.8 g of water was distilled off. (0049) The reaction product was allowed to cool, forming crystals, and then filtered under suction. The very fine precipitate was dried. 18.7 g of a white substance at 78.6 % yield was recovered. IR confirmed that the reaction product was 99% pure.
Statistics shows that 1562-00-1 is playing an increasingly important role. we look forward to future research findings about Sodium isethionate.
Reference:
Patent; GEISTLICH PHARMA AG; PFIRRMANN, Rolf W.; (16 pag.)WO2017/175177; (2017); A1;,
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