Application of 534-03-2, Adding some certain compound to certain chemical reactions, such as: 534-03-2, name is 2-Aminopropane-1,3-diol,molecular formula is C3H9NO2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 534-03-2.
General procedure: A stirred solution of 2-amino-1,3-propanediol (serinol) 1 (1 eq) andtriethylamine in MeOH (10 ml) was cooled at 220C and treateddropwise with a solution of the corresponding acyl chloride (1.1 eq) intetrahydrofurane (THF) (5 ml). The reaction mixture was allowed towarm to room temperature and stirred overnight. Then it was pouredinto brine and extracted with dichloromethane (3 10 ml). Thecombined organic phases were washed with brine, dried over MgSO4,and concentrated under reduced pressure. The residue was purified byflash column chromatography on silica gel using as eluent EtOAc/MeOH (10:1 to 7:1) to provide the corresponding N-acyl serinolderivatives.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 534-03-2, 2-Aminopropane-1,3-diol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Gomez de Cedron, Marta; Vargas, Teodoro; Madrona, Andres; Jimenez, Aranza; Perez-Perez, Maria-Jesus; Quintela, Jose-Carlos; Reglero, Guillermo; San-Felix, Ana; Ramirez de Molina, Ana; Journal of Pharmacology and Experimental Therapeutics; vol. 366; 2; (2018); p. 377 – 389;,
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