The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 41790-30-1, name is (5,6,7,8-Tetrahydronaphthalen-1-yl)methanol. This compound has unique chemical properties. The synthetic route is as follows. name: (5,6,7,8-Tetrahydronaphthalen-1-yl)methanol
To a solution of S5 (5.24 g, 32.3 mmol) in DCM (200 mL) at 0 C was added thionyl chloride (8.45 g, 71.1 mmol). The reaction mixture was stirred at r.t. for 24 h, then solvent was removed under reduced pressure. The residue was diluted with DCM (100 mL) and quenched with ice-water (100 mL). The organic phase was washed with sat. aq. NaHCO3, dried with Na2SO4 and concentrated to give 5-(chloromethyl)-1,2,3,4-tetrahydronaphthalene (S6) as a brown oil (3.25 g, 56%). 1H NMR (CDCl3) delta 7.16-7.05 (m, 3H), 4.59 (s, 2H), 2.86 (t, J = 6.3 Hz, 2H), 2.79 (t, J = 6.4 Hz, 2H), 1.88-1.77 (m, 4H). Found: [M+H]=181.6.
With the rapid development of chemical substances, we look forward to future research findings about 41790-30-1.
Reference:
Article; Sutherland, Hamish S.; Tong, Amy S.T.; Choi, Peter J.; Blaser, Adrian; Conole, Daniel; Franzblau, Scott G.; Lotlikar, Manisha U.; Cooper, Christopher B.; Upton, Anna M.; Denny, William A.; Palmer, Brian D.; Bioorganic and Medicinal Chemistry; vol. 27; 7; (2019); p. 1292 – 1307;,
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