Related Products of 41175-50-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 41175-50-2, name is 1,2,3,5,6,7-Hexahydropyrido[3,2,1-ij]quinolin-8-ol, molecular formula is C12H15NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Phosphorous oxychloride (2.7 mL, 4.4 g, 29 mmol) was added dropwise in flask containing 10 mL DMF for a period of 15 min at 4 C. A solution of 8-hydroxyjulolidine 7 (5.15 g,26.9 mmol) in DMF (5 mL) was then added dropwise to the complex over period of 10 min. When the addition was complete,the reaction was stirred at room temperature for 30 min,and then heated at 100 C for 30 min. After cooling to room temperature, 30 mL of water was added to the stirred dark solution. The aqueous mixture was stirred for 1.5 h resulting in the formation of a blue-green precipitate. The precipitate was isolated by filtration, washed with water and dried. The crude product was purified by column chromatography on silica gel(Toluene/EtOAc, 2:1) Yield = 94 %, m.p. 73-74 C
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 41175-50-2, 1,2,3,5,6,7-Hexahydropyrido[3,2,1-ij]quinolin-8-ol.
Reference:
Article; Chemate, Santosh B.; Sekar, Nagaiyan; Journal of Fluorescence; vol. 25; 6; (2015); p. 1615 – 1628;,
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