Related Products of 6920-22-5 , The common heterocyclic compound, 6920-22-5, name is Hexane-1,2-diol, molecular formula is C6H14O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
Example 1 – Deoxydehyd ration of 1,2-decanediol In the following examples, unless something else is stated, 40 mmol of diol, 2.0 mmol of catalyst (5 mol%, calculated with respect to the amount of vanadium), 500 mg of hexadecane (internal standard), and 100 ml of solvent were mixed in a 300 ml PTFE cup and placed in a 400 ml autoclave with a magnetic stir bar and computer-controlled heating plate. The autoclave was sealed, pressurized with 10-25 bar of H2, N2, or CO and heated to 230 C for 1000 min (corresponding to ~ 16 h at the reaction temperature); the temperature typically stabilized between 225 and 235 C. When the system had cooled to room temperature, the pressure was released, the reaction mixture was filtered to remove a black precipitate and analyzed by GC (for determination of conversion and yields) and GC-MS (for observation and identification of other products). Comparison of solvents A number of primary or secondary monohydric Ci-Cio alcohol solvents were tested together with NH4V03 as the catalyst. In addition, their performance was compared to that of acetone and hexane as solvents. The yields of 1-decene (C=C), 2-decanone (C=0), 2-decanol (2OH), and 1-decanol (lOH) are provided below in Table 1. It is evident that using a primary or secondary monohydric Ci-Cio alcohol as the solvent results in a better selectivity of 1-decene than any of the comparative solvents.
The synthetic route of 6920-22-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; DANMARKS TEKNISKE UNIVERSITET; DETHLEFSEN, Johannes Rytter; FRISTRUP, Peter; (30 pag.)WO2016/101958; (2016); A1;,
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