Electric Literature of 4654-39-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 4654-39-1, name is 2-(4-Bromophenyl)ethanol. This compound has unique chemical properties. The synthetic route is as follows.
Dissolve 31.56g of iodine, 33.91g of triphenylphosphine and 22.35mg of imidazole in anhydrous dichloromethane (100mL), After 30 minutes in an ice bath, 20 g of p-bromobenzyl alcohol was dissolved in anhydrous dichloromethane (50 mL) and quickly added dropwise to the reaction bottle. Remove the ice bath and react at room temperature for about 6 hours. Dichloromethane was distilled off, the reaction liquid was transferred to a separatory funnel, a water-methanol mixed solution (400 mL, water: methanol volume ratio of 1:3) was added, n-heptane extraction (150 mL×3) was added, and shaken vigorously until The whole system is colorless and transparent, and the organic layer is combined. The organic layer was dried over anhydrous sodium sulfate, and the organic solvent was distilled off to obtain a colorless solid, that is, compound 10. The product was stored in the dark and the yield was 93.2%.
According to the analysis of related databases, 4654-39-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Chen Si; Shi Zeyu; Xiao Qiong; Zhang Xiang; Tian Yulin; Yin Dali; (13 pag.)CN111087356; (2020); A;,
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