Synthetic Route of 2568-33-4, Adding some certain compound to certain chemical reactions, such as: 2568-33-4, name is 3-Methylbutane-1,3-diol,molecular formula is C5H12O2, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2568-33-4.
Step 1: 4-Chloro-2-methyl-butan-2-ol 10.0 g (96.0 mmol)_3-methyl-1 ,3-butandiol is dissolved in 30.0 ml toluene and 10.7 g (106 mmol) TEA is added. The funnel is rinsed with 10.0 ml toluene. The mixture is heated to 80C and a mixture of 1 1 .6 g (101 mmol) methanesulfonyl chloride and 3.00 ml toluene is added. After complete addition, the funnel is rinsed with 7.00 ml toluene and the reaction mixture is heated to reflux for approx. 3h. After full conversion (GC) the mixture is cooled to 20 C and 40.0 ml water is added. Stirring is continued for a short period and the aqueous phase is separated. Then, approx. 10 ml of the organic phase is distilled off in vacuum. The crude toluene solution of the product is used for the next step.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2568-33-4, 3-Methylbutane-1,3-diol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; DAHMANN, Georg; WAGNER, Holger; ECKHARDT, Matthias; FRANK, Markus; SANTAGOSTINO, Marco; SCHNAUBELT, Juergen; STERTZ, Uwe; PACHUR, Thorsten; WO2015/44073; (2015); A1;,
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