Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1805-32-9, name is 3,4-Dichlorobenzyl alcohol. This compound has unique chemical properties. The synthetic route is as follows. Product Details of 1805-32-9
Examples 204-206 were prepared according to the method described below: 6′-[(3R)-3-{[tert-Butyl(dimethyl)silyl]oxy}pyrrolidin-1-yl]-2-oxo-2H-1,3′-bipyridin-4-yl 4-bromobenzenesulfonate from Preparation 47 (197 mg, 0.324 mmol), the appropriate benzyl alcohol (0.982 mmol) and potassium hydroxide (55 mg) in DMSO (3 ml) were heated at 130 C. under nitrogen for 1 hour then allowed to stand at r.t. overnight. The reactions were diluted with methanol (3 ml) and passed down a SCX column, washed with methanol and the product eluted with 2M NH3 in methanol, evapourated to dryness. The residue was chromatographed on Biotage 12×150 mm silica column eluting with DCM/MeOH/NH3 98/2/0 to 93/7/1. Solvent removed in vacuo to give the title compound as solids. 204 LC-MS RT = 1.20 min m/z (APCI & ESI) 432 [MH+](2 min run)
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Reference:
Patent; Pfizer Inc; US2008/85884; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts