Reference of 101597-25-5, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 101597-25-5 as follows.
Step 6; To the product in toluene from Step 5, 1 )1 -bis{4~methoxypr¾enyl)prop-2-yn-1 -ol {0.8 g), a few crystals of p-toiuene sulfonic acid were added. After stirring for one hour at room temperature, all the solvent was. evaporated. The recovered product was purified by ComfaiFlash followed by re-crystailization. from diethyl ether. White crystals {0.95 g) were obtained as the product. NMR indicated that the product had a structure consistent with 3,3- bis(4-rrtethoxyphenyl)~l 0, 12-dibromo-6,7-dimethoxy-11 ,13, 13-trimethyl-3H,l 3H- indeno^’.^^jnaphthop ,2-b]pyran as represented by the following graphic formula.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,101597-25-5, its application will become more common.
Reference:
Patent; TRANSITIONS OPTICAL, INC.; WO2012/82506; (2012); A1;,
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