Reference of 90369-75-8, Adding some certain compound to certain chemical reactions, such as: 90369-75-8, name is (3-Chloro-2-methylphenyl)methanol,molecular formula is C8H9ClO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 90369-75-8.
To a solution of phosphorus tribromide (0.422 mL, 4.47 mmol) in Toluene (30 mL) was added (3-chloro-2-methylphenyl)methanol (2 g, 12.77 mmol). The reaction was stirred at RT overnight. The solvent was removed and the residue was partitioned between EtOAc and brine. The organic layer was concentrated and the residue was purified by biotage (5% EA/hexane) to give the product (2.Og, 71%). 1H NMR (400 MHz, CDC13) deltappm 7.36 (m, IH), 7.24 (m, IH), 7.12 (m, IH), 4.56 (s, 2H). 2.48 (s, 3H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 90369-75-8, (3-Chloro-2-methylphenyl)methanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; GLAXOSMITHKLINE LLC; LIN, Hong; LUENGO, Juan, I.; RIVERO, Ralph, A.; SCHULZ, Mark, James; XIE, Ren; ZENG, Jin; WO2010/135504; (2010); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts