Synthetic Route of 53463-68-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 53463-68-6, name is 10-Bromodecanol. This compound has unique chemical properties. The synthetic route is as follows.
(10-Bromo-decyloxy)-t-butyl-dimethyl-silane. To a stirred solution of 10-bromo- decanol (2.44 g, 10.3 mmol) in NMP (13 mL) at 0 C, TBSCI (1.66 g, 11.0 mmol) was added followed by imidazole (0,716 g, 10,5 mmol) portion wise (3 x 0,200 g & 1 x 0,116 g) in 15 min intervals. After the last portion of imidazole had been added, the reaction was stirred for an additional 2 h at 0 C and then it was poured into water (100 mL). The product was extracted into pentane (100 mL), the’organic phase-was concentrated/7 ? vacuo (20 mbar, 50 C) and the crude liquid was purified by filtration through a short silica gel column, using 1: 9 MTBE : petroleum benzene as eluent. The product was obtained as a colorless liquid (3.12 g, 8. 88 mmol, 86% yield based on 10-bromo-decan-1-ol). Reaction conditions were not optimized.
According to the analysis of related databases, 53463-68-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DSM IP Assets B.V.; WO2005/47223; (2005); A1;,
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