Reference of 702-23-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.702-23-8, name is 2-(4-Methoxyphenyl)ethanol, molecular formula is C9H12O2, molecular weight is 152.19, as common compound, the synthetic route is as follows.
Reactant: 6. To a stirred solution of compound 6 (1.0 g, 6.57 mmol) in toluene (40 mL) triethylamine(2.0 mL, 19.71 mmol) was added at 0 C. TsCl (1.5 g, 7.88 mmol) was added slowly and the reaction mixture stirred 48 h at RT. The solution was diluted with diethyl ether and washed with saturatedaqueous NaHCO3 (20 mL). The residue of unreacted precipitated TsCl was filtered out and organiclayer was dried, filtered and concentrated to give light yellow crystals: 29 (2.0 g, 99 %).
The chemical industry reduces the impact on the environment during synthesis 702-23-8, I believe this compound will play a more active role in future production and life.
Reference:
Article; Blaess, Markus; Bibak, Nelly; Claus, Ralf A.; Kohl, Matthias; Bonaterra, Gabriel A.; Kinscherf, Ralf; Laufer, Stefan; Deigner, Hans-Peter; European Journal of Medicinal Chemistry; vol. 153; (2018); p. 73 – 104;,
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