Related Products of 6971-51-3, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.6971-51-3, name is (3-Methoxyphenyl)methanol, molecular formula is C8H10O2, molecular weight is 138.16, as common compound, the synthetic route is as follows.
General procedure: In a 25 mL round bottomed flask were placed 0.1 mol % of copper(I) catalyst, 1 mmol of alcohol, 1 mmol of amine, 0.2 mmol of KOH and 2 mL of toluene. The reaction flask was heated at 100 C for 12 h in an oil bath. Upon completion (as monitored by TLC), the reaction mixture was cooled at ambient temperature, H2O (3 mL) was added and the organic layer was extracted with CH2Cl2 (3 10 mL). The combined organic layers were dried with magnesium sulphate and concentrated. The crude product was purified by column chromatography (ethyl acetate/hexane). Reported isolated yields are an average of two runs
The chemical industry reduces the impact on the environment during synthesis 6971-51-3, I believe this compound will play a more active role in future production and life.
Reference:
Article; Ramachandran, Rangasamy; Prakash, Govindan; Vijayan, Paranthaman; Viswanathamurthi, Periasamy; Grzegorz Malecki, Jan; Inorganica Chimica Acta; vol. 464; (2017); p. 88 – 93;,
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