In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 4845-50-5, name is 1,4-Dioxane-2,3-diol, the common compound, a new synthetic route is introduced below. HPLC of Formula: C4H8O4
To a solution of the corresponding compound 39G (0.9 mmol) in ethanol/water (30 mL/4 mL) was added l,4-dioxane-2,3-diol (130 mg, 1.08 mmol) and the resulting suspension was stirred at 30C overnight. The solvent was removed in vacuo and the residue was partitioned between water and EtOAc. The organic layer was separated and washed with water and brine, dried over Na2S04 and concentrated, and then purified by a standard method to give title product 39H.
The synthetic route of 4845-50-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; AGIOS PHARMACEUTICALS, INC.; CIANCHETTA, Giovanni; POPOVICI-MULLER, Janeta; ZAHLER, Robert; CAO, Sheldon; WANG, Xiaolei; YE, Zhixiong; WO2014/139325; (2014); A1;,
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