Electric Literature of 5182-44-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5182-44-5, name is 2-(3-Chlorophenyl)ethanol. This compound has unique chemical properties. The synthetic route is as follows.
2-(3-chlorophenyl)ethanol (20 g) was treated with benzyltrimethylammonium hydroxide (Triton B) (2.67 mL) and the resultant mixture was stirred in vacuo for 30 minutes. The mixture was then cooled to O0C and treated with t-butyl acrylate (17.40 g). The reaction was warmed to room temperature and stirred for 16 hours. The mixture was filtered through aluminium oxide (15 g) eluting with ether (75 mL). The collected filtrate was concentrated to give the sub-titled compound (34.40 g) as an oil. 1H NMR (CDCl3) delta 7.26-7.07 (m, 4H), 3.69-3.59 (m, 4H), 2.86-2.81 (t, 2H), 2.50-2.45 (t, 2H), 1.43 (s, 9H)
According to the analysis of related databases, 5182-44-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2008/96119; (2008); A1;,
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