Share a compound : 2568-33-4

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 2568-33-4, 3-Methylbutane-1,3-diol.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2568-33-4, name is 3-Methylbutane-1,3-diol. This compound has unique chemical properties. The synthetic route is as follows. category: alcohols-buliding-blocks

(210a) 3-Hydroxy-3-methylbutanal Pyridinium chlorochromate (2.6 g, 12 mmol) and Celite (5 g) were sufficiently ground in a mortar and were suspended in methylene chloride (50 mL). To this mixture, a methylene chloride solution (10 mL) of 3-methyl-1,3-butanediol (1.1 g, 10 mmol) was added. The resulting mixture was stirred at room temperature for 3 hr and then filtered. The filtrate was concentrated under reduced pressure. The resulting crude product was purified by silica gel column chromatography (Biotage, eluding solvent; hexane: ethyl acetate = 2: 3) to obtain 0.47 g (yield: 45%) of the title compound as a colorless oily material. 1H-NMR (400 MHz, CDCl3) delta ppm: 9.85 (1H, t, J = 2.0 Hz), 2.63 (2H, d, J = 2.0 Hz), 1.34 (6H, s).

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 2568-33-4, 3-Methylbutane-1,3-diol.

Reference:
Patent; Sankyo Company, Limited; EP1798229; (2007); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts