The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 627-18-9, name is 3-Bromopropan-1-ol. This compound has unique chemical properties. The synthetic route is as follows. name: 3-Bromopropan-1-ol
General procedure: To a solution of DHA (10.0 mmol) and 2-bromoethanol (10.0 mmol) in CH2Cl2 (30 mL), boronfluoride ethyl ether (0.5 mL) was added dropwise at 0 C. The reaction mixture was stirred at 0 Cfor 8 h, then washed with saturated NaHCO3 solution (20 mL x 3). The organic layer was dried overanhydrous Na2SO4 and concentrated under reduced pressure. The crude products were purified bysilica gel column chromatography (PET/EtOAc = 10:1, v/v) to get the target compound 7a.The compounds 7b and 9a were synthesized by the same operation procedure of compound 7a.
With the rapid development of chemical substances, we look forward to future research findings about 627-18-9.
Reference:
Article; Tian, Ye; Liang, Zhen; Xu, Hang; Mou, Yanhua; Guo, Chun; Molecules; vol. 21; 6; (2016);,
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