New downstream synthetic route of 24034-73-9

The synthetic route of 24034-73-9 has been constantly updated, and we look forward to future research findings.

Adding a certain compound to certain chemical reactions, such as: 24034-73-9, (2E,6E,10E)-3,7,11,15-Tetramethylhexadeca-2,6,10,14-tetraen-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C20H34O, blongs to alcohols-buliding-blocks compound. HPLC of Formula: C20H34O

N–chlorosuccinimide(1.2g,1.3equiv)wassuspendedindryCH2Cl2(15ml).Thesuspensionwascooledto–30C(acetone/liquidN2bath)andafterstirringfor5min,dimethylsulfide(750mul,1.5equiv)wasadded.Thereactionwasstirredfor10minat–30Cand10minat0C.Thenthesolutionwascooledto–40C.Asolutionofgeranylgeraniol(2g,6.9mmol)inCH2Cl2(dry,5ml)wasaddeddropwise.Theresultingsuspensionwasallowedtowarmduring150minto0C,turningintoacloudysolutionat–15C.Thereactionmixturewaspouredintopentane(150ml),Theorganiclayerwaswashedwithwater(2x50ml),brine(50ml),driedoverMgSO4andevaporated.Thereactionafforded1.94gofgeranylgeranylchlorideasacolorlessliquidwhichwasusedwithoutfurtherpurification.

The synthetic route of 24034-73-9 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Jain, Samta; Caforio, Antonella; Fodran, Peter; Lolkema, Juke S.; Minnaard, Adriaan J.; Driessen, Arnold J.M.; Chemistry and Biology; vol. 21; 10; (2014); p. 1392 – 1401;,
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