Introduction of a new synthetic route about Methyl 3-bromo-5-(hydroxymethyl)benzoate

The chemical industry reduces the impact on the environment during synthesis 307353-32-8, I believe this compound will play a more active role in future production and life.

Reference of 307353-32-8, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.307353-32-8, name is Methyl 3-bromo-5-(hydroxymethyl)benzoate, molecular formula is C9H9BrO3, molecular weight is 245.07, as common compound, the synthetic route is as follows.

A mixture of methyl 3-bromo-5-(hydroxymethyl)benzoate (149 mg, 0.61 mmol) and manganese(IV) oxide (529 mg, 6.08 mmol), and CH2Cl2 (3 mL) was stirred at rt overnight. The mixture was filtered through Celite and the filter cake was washed with CH2Cl2. The filtrate was concentrated to afford the title compound.

The chemical industry reduces the impact on the environment during synthesis 307353-32-8, I believe this compound will play a more active role in future production and life.

Reference:
Patent; RENOVIS, INC.; WO2009/110985; (2009); A2;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts