Adding a certain compound to certain chemical reactions, such as: 7735-42-4, 1,16-Hexadecanediol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 7735-42-4, blongs to alcohols-buliding-blocks compound. Recommanded Product: 7735-42-4
Synthesis Example C-(18) 1,16-Hexadecanediol (13.75 g) was dissolved in 37 ml of cyclohexane, and 57% hydrobromic acid solution (37 ml) was added to this solution. The reaction mixture was refluxed for six hours while stirring. After the reaction, the mixture was extracted three times with diethyl ether. The organic layer was neutralized with saturated sodium hydrogen carbonate solution, washed with saline solution, dried over magnesium sulfate, and filtered, and the solvent was distilled off under reduced pressure. Purification of the residue by silica gel flash chromatography (hexane: ethyl acetate = 7:3) gave 16-bromohexadecan-1-ol as white crystals at a 67% yield. Molecular weight: 320.9 (C16H33BrO) TLC: (hexane-ethyl acetate 7-3) Rf value=0.53 1H-NMR: (300MHz, CDCl3)delta: 1.26 (s large, 24H, -(CH2)12-); 1.56 (qt, 2H, J=7.2Hz, -CH2-); 1.85 (qt, 2H, J=7.1 Hz, -CH2-); 3.40 (t, 2H, J=7.1Hz, -CH2-Br); 3.63 (t, 2H, J=6.6Hz, -CH2-O-) 13C-NMR: (75MHz, CDCl3) delta: 25.84; 27.28; 28.22; 29.48-29.50; 32.90; 33.20; 34.01; 63.01
At the same time, in my other blogs, there are other synthetic methods of this type of compound,7735-42-4, 1,16-Hexadecanediol, and friends who are interested can also refer to it.
Reference:
Patent; Meiji Dairies Corporation; EP1854777; (2007); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts