Electric Literature of 3344-77-2, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.3344-77-2, name is 12-Bromododecan-1-ol, molecular formula is C12H25BrO, molecular weight is 265.23, as common compound, the synthetic route is as follows.
To a solution of S1 (680 mg, 2.58 mmol) in CH2Cl2 (4.6 mL) were added 3,4-dihydro-2H-pyran (0.35 mL, 3.89 mmol) and pyridinium p-toluene sulfonate (6.59 mg, 26.2 mumol). The reaction mixture was stirred at room temperature for 4 h and then diluted with CH2Cl2. The resulting mixture was washed with sat. NaHCO3 and brine, dried over MgSO4, and evaporated. The resulting residue was purified by column chromatography (SiO2, hexane:EtOAc 30/1) to furnish S2 (763 mg, 85percent) as a colorless oil
Statistics shows that 3344-77-2 is playing an increasingly important role. we look forward to future research findings about 12-Bromododecan-1-ol.
Reference:
Article; Takagi, Ryukichi; Igata, Nao; Yamamoto, Kazuhiro; Kojima, Satoshi; Journal of Organometallic Chemistry; vol. 696; 8; (2011); p. 1556 – 1564;,
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