Related Products of 149965-40-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 149965-40-2, name is (5-Bromo-2-chlorophenyl)methanol, molecular formula is C7H6BrClO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
60 g PCC and 60 g silica gel powder were added to a round bottom flask; after mixing, 500 mL dichloromethane was added; cooled to 0 C., and 45 g of compound 1-1 in dichloromethane (300 mL) was added dropwise with stirring; maintaining 0 C.The reaction was monitored by TLC; after the reaction was completed, the reaction solution was spin-dried; 38 g of Compound 1-2 was isolated by column separation, and the yield in two steps was 90%.
According to the analysis of related databases, 149965-40-2, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Guangzhou Medical University; Hu Wenhui; Yu Xiyong; Zhao Xin; Wu Bo; (25 pag.)CN107556276; (2018); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts