Extracurricular laboratory: Synthetic route of 1,2-Pentanediol

According to the analysis of related databases, 5343-92-0, the application of this compound in the production field has become more and more popular.

Electric Literature of 5343-92-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5343-92-0, name is 1,2-Pentanediol. This compound has unique chemical properties. The synthetic route is as follows.

IFO therefore was electrochemically oxidized in acetonitrile in the presence of various alcohols with 5 carbon atoms. The reaction was stopped when all the starting material appeared to be consumed as monitored by TLC. At the end of the reaction, sodium bicarbonate (1 Eq.) was added to the medium to neutralize electrogenerated hydrons. The proportions of the various diastereomers were determined on the crude reaction mixture by 31P-NMR before being isolated by ?flash chromatography?.

According to the analysis of related databases, 5343-92-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; INSTITUT GUSTAVE ROUSSY; Paci, Angelo; Martens, Thierry; Rivard, Michael; Couvreur, Patrick; Desmael, Didier; Caron, Joachim; US2013/261088; (2013); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts