Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1475-13-4, name is 1-(2,4-Dichlorophenyl)ethanol. A new synthetic method of this compound is introduced below., Computed Properties of C8H8Cl2O
General procedure: A mixture of 2 mmol of substrate, and 4 mL ethylene glycol was stirred for 5 min, and then 2.4 mmol of DBDMH or 4.6 mmol of NBS was added by 5 times in one hour, and the mixture was stirred 24 h at room temperature. Afterward, the mixture was extracted with ether (10 mL × 3). The combined organic layer was washed twice by water (20 mL), and dried over anhydrous Na2SO4. After filtration, the solvent was removed under reduced pressure, and the residual was treated with alumina chromatography (Petroleum ether/AcOEt=20/1,V/V) to generate the product.
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 1475-13-4, 1-(2,4-Dichlorophenyl)ethanol.
Reference:
Article; Han, Bingbing; Zheng, Zubiao; Wu, Fang; Wang, Aidong; Synthetic Communications; vol. 47; 24; (2017); p. 2387 – 2394;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts