In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 109-83-1, name is 2-(Methylamino)ethanol, the common compound, a new synthetic route is introduced below. Quality Control of 2-(Methylamino)ethanol
15.1 A solution of 20.0 g (266.3 mmol) of 2-(methylamino)ethanol was dissolved in 100 mL of CH2Cl2 and treated first with 74.23 mL (532.54 mmol, 2 eq) of Et3N then with 33.8 mL (239.64 mmol, 0.9 eq) of benzylchloroformate within a period of 1.5 h at RT. The reaction was partitioned between Et2O (*3)/aqueous 10% KHSO4 (*2), dried over Na2SO4 and evaporated to yield 37.93 g (68%) of (2-hydroxy-ethyl)-methyl-carbamic acid benzyl ester, MS: 210 (MH+).
The synthetic route of 109-83-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Ackermann, Jean; Aebi, Johannes; Dehmlow, Henrietta; Hirth, Georges; Maerki, Hans-Peter; Morand, Olivier; Panday, Narendra; US2005/65210; (2005); A1;,
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