Reference of 37729-18-3, Adding some certain compound to certain chemical reactions, such as: 37729-18-3, name is 2-([1,1′-Biphenyl]-4-yl)ethanol,molecular formula is C14H14O, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 37729-18-3.
2-biphenyl ethanol (1 g, 5 mmol), 4-nitrophenol (834 mg, 6 mmol), andtriphenylphosphine (1.59 g, 6 mmol) was dissolved in 20 mL dichloromethane. Thesolution was chilled in an ice-water bath prior to the addition of diethylazodicarboxylate(949 i, 6 mmol). The reaction was then stirred overnight, and the ice-water bath slowlywarmed to room temperature. Crude product was purified by flash chromatography toyield 640 mg crystalline solid. ]H NMR (400 MHz, DMSO-d6) 5 8.1 (d), 7.6 (m), 7.47-7.41 (m), 7.34 (m), 7.17 (m), 4.39 (t, 2H), 3.13 (t, 2H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 37729-18-3, 2-([1,1′-Biphenyl]-4-yl)ethanol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; PRAECIS PHARMACEUTICALS, INC.; WO2006/20951; (2006); A1;,
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