Adding a certain compound to certain chemical reactions, such as: 22436-06-2, (S)-2-Methyl-3-phenylpropan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 22436-06-2, blongs to alcohols-buliding-blocks compound. Quality Control of (S)-2-Methyl-3-phenylpropan-1-ol
General procedure: To a CH2Cl2 solution (0.8mL) of the (Sax)-chloride 1b (118mg,0.2 mmol) was added a solution of 2-methyl-1-hexanol (1a)(71.7 mg, 0.6 mmol) in CH2Cl2 (0.8 mL) and Et3N (0.03 mL,0.2 mmol) at room temperature under an Ar atmosphere. Theresulting solution was stirred at reflux in CH2Cl2 for 7 hr. Thereaction mixture was poured into water and extracted withCH2Cl2. The organic layer was dried over MgSO4, filtered, concentrated,and purified by column chromatography on silicagel (CH2Cl2:hexane = 1:5) to give the corresponding ester 5a(71.3 mg, 53%, 50:50) as a white solid.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,22436-06-2, its application will become more common.
Reference:
Article; Murai, Toshiaki; Itoh, Hikaru; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 191; 2; (2016); p. 163 – 173;,
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