Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 7287-81-2, name is 1-(m-Tolyl)ethanol. A new synthetic method of this compound is introduced below., Safety of 1-(m-Tolyl)ethanol
The racemic alcohol (1r) at -30 C1.0 mmol as a catalyst was dissolved in 5 ml dichloromethane (wherein, R I andn is 2; and pharmaceutically acceptable salts thereof) compound of the formula(1) was added 0.01 mol% and the potassium fluoro one equivalent of fluoride, acarboxylic acid group and the ion exchange resin 80 mg silylating agent offormula (5), including (in the formula, R is methyl) was added to 0.7equivalents, and then the mixture was stirred for 1 hour. Filtering the mixturewas concentrated and then to recover the potassium fluoride and the ionexchange resin. The residue was purified by flash chromatography (acetone /hexane / triethylamine = 1: 5: 0.025) to give the chiral alcohol; to give the(2r, yield 47% 98% ee, (R) -form).
If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 7287-81-2, 1-(m-Tolyl)ethanol.
Reference:
Patent; RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY; SONG, CHOON GEUI; PARK, SANG YEON; LEE, JI WOONG; (43 pag.)KR2015/114445; (2015); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts