Application of 101597-25-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.101597-25-5, name is 1,1-Bis(4-methoxyphenyl)prop-2-yn-1-ol, molecular formula is C17H16O3, molecular weight is 268.31, as common compound, the synthetic route is as follows.
Step 5 4-Methylbenzenesulfonic acid (3mg) was added to a stirring mixture containing the product from Step 4 (0.042g), and 1 ,1-bis(4-methoxyphenyl)prop- 2-yn-1-ol (0.066g) in 1 ,2-dichloroethane (5mL). After stirring for two hours, the mixture was washed with water, followed by extraction of the aqueous fraction with ethyl acetate, and drying the combined organic fractions over sodium sulfate. The volume of the organic mixture was reduced under vacuum and the crude residue was purified by column chromatography. The NMR of the orange solid was consistent with 2,2-bis(4-methoxyphenyl)-2H- benzo[f]thieno[2′,3′:4,5]thieno[3,2-h]chromene (0.063g).
Statistics shows that 101597-25-5 is playing an increasingly important role. we look forward to future research findings about 1,1-Bis(4-methoxyphenyl)prop-2-yn-1-ol.
Reference:
Patent; TRANSITIONS OPTICAL, INC.; DENG, Jun; STEPP, Brian, R.; SPITLER, Eric; XIAO, Wenjing; TAMASULO, Massimiliano; WALTERS, Robert, W.; (140 pag.)WO2016/144324; (2016); A1;,
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