Introduction of a new synthetic route about 3,3-Diphenyl-1-propanol

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,20017-67-8, its application will become more common.

Adding a certain compound to certain chemical reactions, such as: 20017-67-8, 3,3-Diphenyl-1-propanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 20017-67-8, blongs to alcohols-buliding-blocks compound. Product Details of 20017-67-8

Example 13 3-[4-(3,3-Diphenyl-propoxy)-phenyl]-2-ethoxy-propionic acid ethyl ester Reaction of 3,3-diphenyl-propan-1-ol (110 mg, 0.5 mmol), triphenylphosphine (145 mg, 0.55 mmol), 2-ethoxy-3-(4-hydroxy-phenyl)-propionic acid ethyl ester (140 mg, 0.6 mmol) and diethylazodicarboxylate (0.09 mL, 0.55 mmol) in an identical manner to Example 1 gave the title compound (120 mg). 1H NMR (CDCl3, 300 MHz); delta 1.10-1.29 (6H, 2*CH3), 2.44-2.55 (2H, CH2), 2.90-2.95 (2H, CH2), 3.28-3.39 and 3.51-3.62 (2H, OCH2), 3.80-3.89 (2H, CH2), 3.90-3.95 (1H, CHCO2), 4.10-4.28 (3H, arylCH and OCH2), 6.70-6.77 (2H, aryl), 7.05-7.35 (remaining H, aryl). MS calcd for C28H32O4 432.6, Found 432.3.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,20017-67-8, its application will become more common.

Reference:
Patent; Novo Nordisk, A/S; US6972294; (2005); B1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts